Such Bad Popeye, Should I Medicate Or No? Epsom Salt Or No?

Hello,
First I'd like to thank any and all for taking there time to read this and possibly help me, I'm very overwhelmed and confused after spending hours searching the web and YouTube alike, every page/video seems to know exactly what to do and they all make it point to say what everyone else does is wrong so I'm left unanswered, confused and worried cuz meanwhile the eye is just getting worse and worse.....
First I'll start with the basics, I've been in the Freshwater hobby for about 3 almost 4 years and never had any issue till now, I was recently out of town for a month and had a fish sitter and I am starting to think they didn't do as good as job as they claimed with changing the water....
TANK: 48 Gal glass Bowfront
HOW LONG: This tank has been cycled with no issues for 1.5 yrs. (with most of the same fish)
INHABITANTS: ~Angel (3", I got from someone who couldn't care for it and didn't know anything about it and that was about him 2 yrs ago, he was sick when she gave to me, she brought him to me in a sandwich baggie so needless to say he had it bad before) ~Zebra Loach 2.5" 3yrs ~Dwarf Neon Rainbow 1.5" 2yrs ~Madagascar Rainbow 3" 1yr (alpha, tank boss) ~Upside down Catfish 2" 2 yrs ~2 GloFish 1" 1.5yrs (1 blue 1 purple) ~Turquoise Rainbow 2" 2yrs ~ Betta Fish (Female) 1.5" 1yr * ~African Dwarf Frog 2" .5yr* ~Roseline Shark 3.5" 2.5yrs **

*Haven't seen those two in weeks, I very much hope there hiding
**He Died 2 days ago (5/11) and I am VERY upset about this. He was fine last week. His body looked totally normal. No Idea why died.

SUBSTRATE: Black Sand
PLANTS: Mix of fake and live mixed with random rocks making caves (see pic)
HEATER: Aqueon 150W
FILTER: Fluval 350 External Filter with Filter floss, bio-media, foam, and carbon.
WATER CHANGES: Weekly (now that i'm back) 30% - 40%
CONDITIONER: Prime
CURRENT WATER PARAMETERS (I TESTED TODAY):
TESTER: Tetra Easy Strips, API liquid for pH, Seachem Alert used also for Ph and Ammonia
Temp: 82.1
Nitrate -- 20ppm
Nitrite -- 0ppm
Total Hardness (GH) --25ppm
Total Chlorine -- 0ppm
Total Alkalinity (KH) --40ppm
pH -- 6.8*
*I've been testing 2 times a day if not more and when I woke up this morning around 7 I tested and pH was at 7.5 I don't know how long it was like that as I just got the liquid tester and it's fairly easy to read while the other is not so I treated the ph with API pH down until it got where I wanted then when I did water change I used Seachem Neutral Regulator.

So I think that about covers it as far as all the details go, if I left anything out please feel free to let me know and I'll get the info in there asap.

WHAT HAPPENE Exactly 5 days ago I noticed his eye starting to bulge out and get cloudy, nothing at all bad thou, some much so I didn't think about it till the next day when bam it was bad , he is swimming sideways as well, he's not his normal self as he's obviously sluggish and in pain, I started my research and learned it was a water quality issue since then I've done a 40% water change every other day besides yesterday and today I did both days, his diet has changed at all he's still eating and is poo looks all normal, but his eye is not getting any better, so the weird thing is that Day 2 and 3 during the evening one of my fish (or multiple don't really know) was doing something very strange....at least once every 20 to 30 mins I'd here the water splash, like loudly, which I've honestly never heard them do before but every time I looked I couldn't see who was doing it but someone was going from the bottom and streaking up to the top and doing something then streaking back down, again I couldn't tell you who it was but I would catch them streaking back n forth every so often...I don't think this was my angel which made me think I had another issue on my hands, well that went on for 2 days then I found my Roseline floating at the top with no visible signs of anything wrong.....since that it's stopped. I have a hospital tank set up, a 10 gal with a foam filter and heater and light but honestly I went to move my angel in there today and he is so fidgety from the bucket (he's always been that way) that in his maneuvers to get away from me I felt he was doing more damage to his eye than it was even worth so I just stopped so for now he's not in the hospital tank, I've continued to do water changes on the QT tank the same time as normal tank just as if there was a fish in there...So I have PrazI Pro here at the house which seems like it would be good for a 5 day treatment maybe? I also have easily accessible Epsom salt (the grocery store is 3 mins away from me where I can get anytime) which seems like it would work but would I do a bath or put it in the tank and if so how much what do I do all those good questions.....Lastly I have Marineland All-In-One remedy medication which comes in pill form and says attacks broad range of fish diseases treats external parasites, viral, fungal and bacterial infections. So it would seem as if that would work as well, then some people say just keep up the h20 changes and it will take care of itself....which is not happening so far.

So I guess my questions are is my tank ok? What to do with Angel,qt or no? Which medication should I use and for long with how many water changes and anything else you guys think would prove helpful for me.....

Again I thank you very much to anyone that takes time out of there day to help me with this, I'm super overwhelmed by the vast amount of info available and while I understand not one person is going to be totally correct and I'm sure there are multiple ways to treat that work I just don't want to do anything wrong and make it worse so ya again any help would be great, thank you and I appreciate all ya'lls knowledge very much !!!!

 

Wow! Welcome and I’m so sorry for your angel and the loss of your shark. Question, how long have you had this particular ammonia alert. Seachem also has an ammonia test kit that test for free ammonia as well as total. Just info.
Water changes yes definitely. Since you can’t find the frogs I wouldn’t use salt. I know guys, don’t pass out. (My first line of defense is salt because I’ve had such good luck with it). But I think yours has gone a bit beyond first line. Can you get kanamycin and furan 2? Together they make a wonderful cure for popeye. The frogs will be ok with it as well. If you have snails (you didn’t mention any I think) take them out. Others may have more to add. But maybe this will start you off getting your angel well. Keep us posted? Please?

 

If you're brave enough you could perform an operation on the popeyed fish. I don't believe there is any other way to treat this. Or maybe there is. Don't take my word for it.

 

Be aware that popeyed disease can be difficult to treat. It's caused by infection causing fluid to build up behind the eye causing it to bulge out. I would quarantine the fish first. The all in one treatment should be used along with 1 to 3 tsp of epson salts. The epson salt will help bring down the swelling and the other will actually treat the infection over the course of about a week. Your main tank will need to have several partial water changes during that time vacuuming it from the bottom to get the water conditions as pristine as possible. Even though the fish will be completed with treatment in a week, could possibly take a month for the swelling to completely go away. The cloudiness of the eye's cornea should clear up too, but in some severe cases, the cornea may be too badly damaged. When you do your water changes while the fish is in quarantine, do 25 percent everyday. Once the fish is replaced to the main tank, make sure you continue 25 percent water changes at least once a week and keep a close watch on water perameters. If ammonia or ntrites spike before your scheduled weekly changes, then go ahead and do a water change immediately. Be careful of overfeeding. Popeye infection and other pathogens are more opportunistic during fowl water conditions.

Hello,
First I'd like to thank any and all for taking there time to read this and possibly help me, I'm very overwhelmed and confused after spending hours searching the web and YouTube alike, every page/video seems to know exactly what to do and they all make it point to say what everyone else does is wrong so I'm left unanswered, confused and worried cuz meanwhile the eye is just getting worse and worse.....
First I'll start with the basics, I've been in the Freshwater hobby for about 3 almost 4 years and never had any issue till now, I was recently out of town for a month and had a fish sitter and I am starting to think they didn't do as good as job as they claimed with changing the water....
TANK: 48 Gal glass Bowfront
HOW LONG: This tank has been cycled with no issues for 1.5 yrs. (with most of the same fish)
INHABITANTS: ~Angel (3", I got from someone who couldn't care for it and didn't know anything about it and that was about him 2 yrs ago, he was sick when she gave to me, she brought him to me in a sandwich baggie so needless to say he had it bad before) ~Zebra Loach 2.5" 3yrs ~Dwarf Neon Rainbow 1.5" 2yrs ~Madagascar Rainbow 3" 1yr (alpha, tank boss) ~Upside down Catfish 2" 2 yrs ~2 GloFish 1" 1.5yrs (1 blue 1 purple) ~Turquoise Rainbow 2" 2yrs ~ Betta Fish (Female) 1.5" 1yr * ~African Dwarf Frog 2" .5yr* ~Roseline Shark 3.5" 2.5yrs **

*Haven't seen those two in weeks, I very much hope there hiding
**He Died 2 days ago (5/11) and I am VERY upset about this. He was fine last week. His body looked totally normal. No Idea why died.

SUBSTRATE: Black Sand
PLANTS: Mix of fake and live mixed with random rocks making caves (see pic)
HEATER: Aqueon 150W
FILTER: Fluval 350 External Filter with Filter floss, bio-media, foam, and carbon.
WATER CHANGES: Weekly (now that i'm back) 30% - 40%
CONDITIONER: Prime
CURRENT WATER PARAMETERS (I TESTED TODAY):
TESTER: Tetra Easy Strips, API liquid for pH, Seachem Alert used also for Ph and Ammonia
Temp: 82.1
Nitrate -- 20ppm
Nitrite -- 0ppm
Total Hardness (GH) --25ppm
Total Chlorine -- 0ppm
Total Alkalinity (KH) --40ppm
pH -- 6.8*
*I've been testing 2 times a day if not more and when I woke up this morning around 7 I tested and pH was at 7.5 I don't know how long it was like that as I just got the liquid tester and it's fairly easy to read while the other is not so I treated the ph with API pH down until it got where I wanted then when I did water change I used Seachem Neutral Regulator.

So I think that about covers it as far as all the details go, if I left anything out please feel free to let me know and I'll get the info in there asap.

WHAT HAPPENE Exactly 5 days ago I noticed his eye starting to bulge out and get cloudy, nothing at all bad thou, some much so I didn't think about it till the next day when bam it was bad , he is swimming sideways as well, he's not his normal self as he's obviously sluggish and in pain, I started my research and learned it was a water quality issue since then I've done a 40% water change every other day besides yesterday and today I did both days, his diet has changed at all he's still eating and is poo looks all normal, but his eye is not getting any better, so the weird thing is that Day 2 and 3 during the evening one of my fish (or multiple don't really know) was doing something very strange....at least once every 20 to 30 mins I'd here the water splash, like loudly, which I've honestly never heard them do before but every time I looked I couldn't see who was doing it but someone was going from the bottom and streaking up to the top and doing something then streaking back down, again I couldn't tell you who it was but I would catch them streaking back n forth every so often...I don't think this was my angel which made me think I had another issue on my hands, well that went on for 2 days then I found my Roseline floating at the top with no visible signs of anything wrong.....since that it's stopped. I have a hospital tank set up, a 10 gal with a foam filter and heater and light but honestly I went to move my angel in there today and he is so fidgety from the bucket (he's always been that way) that in his maneuvers to get away from me I felt he was doing more damage to his eye than it was even worth so I just stopped so for now he's not in the hospital tank, I've continued to do water changes on the QT tank the same time as normal tank just as if there was a fish in there...So I have PrazI Pro here at the house which seems like it would be good for a 5 day treatment maybe? I also have easily accessible Epsom salt (the grocery store is 3 mins away from me where I can get anytime) which seems like it would work but would I do a bath or put it in the tank and if so how much what do I do all those good questions.....Lastly I have Marineland All-In-One remedy medication which comes in pill form and says attacks broad range of fish diseases treats external parasites, viral, fungal and bacterial infections. So it would seem as if that would work as well, then some people say just keep up the h20 changes and it will take care of itself....which is not happening so far.

So I guess my questions are is my tank ok? What to do with Angel,qt or no? Which medication should I use and for long with how many water changes and anything else you guys think would prove helpful for me.....

Again I thank you very much to anyone that takes time out of there day to help me with this, I'm super overwhelmed by the vast amount of info available and while I understand not one person is going to be totally correct and I'm sure there are multiple ways to treat that work I just don't want to do anything wrong and make it worse so ya again any help would be great, thank you and I appreciate all ya'lls knowledge very much !!!!

 

Sorry, the 1 to 3 tsps of epson salts is per 5 gallons of water.

Be aware that popeyed disease can be difficult to treat. It's caused by infection causing fluid to build up behind the eye causing it to bulge out. I would quarantine the fish first. The all in one treatment should be used along with 1 to 3 tsp of epson salts. The epson salt will help bring down the swelling and the other will actually treat the infection over the course of about a week. Your main tank will need to have several partial water changes during that time vacuuming it from the bottom to get the water conditions as pristine as possible. Even though the fish will be completed with treatment in a week, could possibly take a month for the swelling to completely go away. The cloudiness of the eye's cornea should clear up too, but in some severe cases, the cornea may be too badly damaged. When you do your water changes while the fish is in quarantine, do 25 percent everyday. Once the fish is replaced to the main tank, make sure you continue 25 percent water changes at least once a week and keep a close watch on water perameters. If ammonia or ntrites spike before your scheduled weekly changes, then go ahead and do a water change immediately. Be careful of overfeeding. Popeye infection and other pathogens are more opportunistic during fowl water conditions.

 

Cant say much because finnipper59 already said what I was gonna say. But, your stocking isn't the best, so that may have not helped the solution. Half of the fish that you have are suppose to be in groups.