Yes, I am the self-proclaimed queen of mycobacteria, telling everyone that full-blown cases of fish TB are rare. More to the point, I have had less than 3% of my current Endler collection come down with full-blown TB. I have been experienced more TB and mycobacteriosis than most people because many of my fish come from a university laboratory where the research on them had been concluded. After I got the fish, I was alerted to the fact that the remaining fish had to be put down due to out-of-control mycobacteriosis, that included both TB and several other diseases. It is very easy for neglected fish to get sick and laboratories. When the research and's, they no longer get continuous attention from graduate students. The livebearers' numbers get out of control, their water parameters go bad, and they are housed in the quarantine room where the sick fish are, where they get contaminated. There is simply not enough time and money to take good care of them. So you are very unlikely to have a situation as out-of-control as mine. I take full responsibility for my situation because I am the worst animal rescuer that you can imagine. (We are down to six dogs at our house at the moment.) And yes, I am planning on starting a thread for others who also are in dire need of a 12-step program for compulsive fish rescuers. (And no, you can't have any of my Endler's unless you can write me a coherent explanation of why and how you will take care of them for life.) I am now managing multiple diseases in seven tanks with varying degrees of success and occasional setbacks. The survival rate has jumped considerably in the past year between several generations of livebearers. I have gone from 0% survival rate in my first experience with TB 35 years ago to 50%, using antibiotics 6 years ago with some fish from an LFS. The remaining fish never thrived and half of them gradually died from secondary infections until I discovered Camallanus worms and finally euthanized them. With the fish from the lab, I have culled for sick fish and used no medications whatsoever. From my observations, they have mostly been contracting columnaris and dropsy. They almost never die of the diseases because I euthanize them whenever possible. The survival rate has been 8% after 12 months with my first generation and over 80% in my second and third generations at between 8 and 11 months. After reading an article by Diana Walstad, I have now begun using level one UV sterilizers to see if I can get better results. I only started using the level one UV sterilizer in the tanks seven weeks ago, so the case of full-blown TB that I found recently cannot be counted against it. At any rate, I have to keep track of the fourth generation over the next year before I can figure out if this new strategy is having enough of an effect. I am aiming for survival rate of 95% at 10 months of age, but I need to get two more tanks set up that are dedicated to this generation alone, and I do not have the resources at this time unless I start euthanizing healthy fish, which I cannot do. No, I am not a biologist, I just know many in various biology departments. I am a daughter and sister of doctors and nurses both in the US and the developing world. So I have seen a lot. And yes, your fish and you can live with multiple mycobacteria.