quoted from another post and hopefully explains a lil more for you ..there is NO nitrobacter in tetra safestart but there is in nite-out which means its no self sustaining...
.TSS and bio spira has something called nitrospira live bacteria (self sustaining live bacteria that will die without
ammonia or fish) and cycle, stress zyme ,fritz zyme, etc has nitrobacter which is in a suspended state(not live on arrival or addition) without an ammonia source(not self sustaining and needs to be added regularly with an ammonia source to wake it up in a sense)