I've got a 'mystery illness' going on in my two new cherry barbs that I got on Feb 14. They've been in
QT for the last 2 weeks while I've been trying to get them all better with (so far) zero progress. For some history, see
here.
A lot of forum members have recommended I use Mardel's Maracyn and Maracyn-2, for gram positive and gram negative bacteria respectively. I was unable to find Maracyn-2 at the time and ended up ordering
API's Furan-2, a broad-spectrum antibiotic for both gram positive and gram negative bacteria. As I have not yet seen mention of this med on FishLore, I thought I'd document my experience with it.
The two cherry barbs have been through a course of Maracyn and a course of Jungle's Anti-Parasite fizz tabs, both with no result. I ran black carbon and did large water changes in between each med. Currently they are depressed, not eating, have clamped dorsal fins, very poor colour, they hide among the plants and have bright red swollen gills. When they do move about they are flicking off objects in the tank. The water was tested recently and has
ammonia 0,
nitrite 0, and (bc of all the wc's) nitrates 0-5. So it isn't ammonia poisoning, and as Jungle's stuff didn't help it isn't gill fluke. It is however exactly the same set of symptoms exhibited by all the fish in my 20g last November, before I found FishLore. They all died. At the experience level I had at that time it never occurred to me to consider 'bacterial gill disease' and try a broad-spectrum antibiotic - their symptoms fit parasitism very well, although meds for that had no effect. Here's hoping I have better luck this time. I will say that these particular fish are NOT going into the 20g until I know for extra-certain-sure that they are healthy and this sickness is kaputsky!
Active ingredients in Furan-2: 60 mg Nitrofurazone and 25 mg Furazolidone per packet (each packet treats 10 g). I am to dose the tank once a day for 2 days, do a 25% WC, repeat for a total of 4 doses; treatment may be repeated. It will NOT harm the biofilter, as stated on the package. This med cost me $11.99 CAD for 10 packets (which means I've spent nearly $30 so far on meds for my two $1.50 fish

I really hope this works).
First dose went in this morning about 45 minutes ago. First thing I noticed is the powder is brilliant yellow. I thought from the name it might be an iron compound, but apparently we have sulfur going on - this is good, I remember sulfur is pretty effective against bacteria. The next thing is that the powder is noticably coarser than Mardel's stuff. Oh well big deal, in it goes. It doesn't dissolve very quickly because of the coarseness, and there are small clumps of it throughout the tank. I use a piece of dowelling to stir these up a bit and they dissolve readily. Interestingly, where a clump fell onto a brown-algae covered silk plant leaf, when I remove the clump the leaf is now clean in that spot. Scary?
The water is YELLOW. Really yellow. I'm a little concerned by this as I would have preferred to verify the 'won't harm the biofilter' claim with water testing, and well if my tests give me results in shades of yellow and the water's yellow to begin with, that's not going to work. I'll have to do it the old fashioned way - watch the fish.
Twenty minutes after first dose - we have movement! The female is cruising around the tank and picking at the gravel! Whoohoo! I hope that lasts. The male moves only slightly - closer to the heater - then starts hovering again. Hopefully he makes it through this, third course of meds has got to be stressful for him.
5g Furan-2 1st day.JPG <--- Pic of the tank. I don't think the yellow colouring is showing up too well though.
male cherry furan-2 1st day.JPG <--- Pic of the male cherry (as good as I could get anyways).
It's only day 1, so we'll see how this goes.