First Coppersafe was worked great against my VERY stubborn case of Ich. No fish or plant loss at all even the pesky pond snails were fine. The cycle remained intact as well.
If I remember correctly though you should not have the heat raised up that high with Coppersafe. The oxygen is already depleted in the water due to the medicine and further depleted by warmer temps. Check on the instructions though as I am not 100% positive.
JDHEF is correct about two types of Maracyn. Coppersafe is safe to mix with other Mardel products but I would be a little nervous about mixing with other brands. Follow the instructions very closely with Coppersafe. Do you have a copper
test kit to monitor copper levels? The same can be said for Maracyn- to be effective you must do it for the entire recommended time. It sounds like you did the first time.