I used to do a thorough vacumm, including moving things around every two weeks in one half of the tank I keep my Oscars.
Since I upgraded my mechanical filtration (
powerhead with attached canister -intended for activated charcoal but filled only with filter floss, placed near substrate level where historically more organic waste ended up) I don't move things around too much. Just the surface cleaning with the vacuum (sand substrate, I don't use gravel) of half side of the tank weekly as I take water out. I do a 50% water change weekly in that 145gal tank. What I do weekly, no matter what, is finding those deep substrate areas (some change location as the Oscars, Severums, Convicts and Kenyi all do their own
aquascaping with the sand) and stir them with the vacuum.
In my other tanks, maintenance is quite easy as far as substrate vacuum and moving decor goes. I lift and clean behind hollow decor that serves as caves for some bottom dwellers once every one or two months. It's amazing how some fish keep the substrate clean (e.g. Silver Dollars, Pandas and Bronze Corydoras and to some degree Kuhli Loaches), and then the inverts cleaning crew: Ghost Srimps, Nerite and Apple Snails.
Pepe
Santo Domingo