Hi Danny, Welcome to Fish Lore
Sorry, I had missed the edit.
I'd suggest you start a new thread to get your question the attention it deserves.
Include the size tank, how long it has been set up, is it cylced and what your readings are for ammonia, nitrite and nitrates.
I don't know about guppies, so I'd only be guessing.
If you added them all at once, it could be they're feeling the effects of the increased bio-load (ammonia).
Start a new thread for a new topic and problem, lots of people here will be happy to help.
Sorry, I couldn't help further.