How long have you had your tank and have you done the
nitrogen cycle on the tank?
http://www.fishlore.com/NitrogenCycle.htm
Do you have the testing equipment to do tests for
ammonia, nitrites, and nitrates?
If so can you give us the results of the tests?
How often do you do water changes and how much - 30% 40% 50%?
What size is the tank?
How many fish do you have in there and what kind?
Are you running an airstone in the tank?
What temperature do you keep the tank at?
What kind of filter do you have in the tank?
I know this is a lot to ask but we really do need the information to give you an intelligent answer. In the meantime, I would do a large (75%
water change) and start an airstone and airpump. This will at least take care of the two main possible problems for a day. (ammonia poisoning in an uncycled tank and oxygen starvation). Also the temperature of the tank should be about 80 degrees for the health of the fish.
Rose